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1

Repackaging Cigarettes — Will the Courts Thwart the FDA?

Bayer, Ronald, Gostin, Lawrence, Marcus-Toll, Daniel

Journal:

Boston Medical and Surgical Journal

Year:

2012

Language:

english

File:

PDF, 799 KB

english, 2012

2

Synthesis, Biological Evaluation, and SAR Studies of 14β-phenylacetyl Substituted 17-cyclopropylmethyl-7, 8-dihydronoroxymorphinones Derivatives: Ligands With Mixed NOP and Opioid Receptor Profile

Kumar, Vinod, Polgar, Willma E., Cami-Kobeci, Gerta, Thomas, Mark P., Khroyan, Taline V., Toll, Lawrence, Husbands, Stephen M.

Journal:

Frontiers in Psychiatry

Year:

2018

Language:

english

File:

PDF, 1.12 MB

english, 2018

3

[Handbook of Experimental Pharmacology] || NOP-Related Mechanisms in Pain and Analgesia

Year:

2019

Language:

english

File:

PDF, 582 KB

english, 2019

4

[3H]Doxepin interactions with histamine H1-receptors and other sites in guinea pig and rat brain homogenates

Vinh Tan Tran, Richard Lebovitz, Lawrence Toll, Solomon H. Snyder

Journal:

European Journal of Pharmacology

Year:

1981

Language:

english

File:

PDF, 642 KB

english, 1981

5

High affinity α3β4 nicotinic acetylcholine receptor ligands AT-1001 and AT-1012 attenuate cocaine-induced conditioned place preference and behavioral sensitization in mice

Khroyan, Taline V., Yasuda, Dennis, Toll, Lawrence, Polgar, Willma E., Zaveri, Nurulain T.

Journal:

Biochemical Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.46 MB

english, 2015

6

In Vitro and In Vivo Profile of PPL-101 and PPL-103: Mixed Opioid Partial Agonist Analgesics with Low Abuse Potential

Khroyan, Taline V., Cippitelli, Andrea, Toll, Nicholas, Lawson, John A., Crossman, William, Polgar, Willma E., Toll, Lawrence

Journal:

Frontiers in Psychiatry

Year:

2017

Language:

english

File:

PDF, 2.18 MB

english, 2017

7

Orphanin FQ/Nociceptin Activates Nuclear Factor Kappa B

Donica, Courtney L., Ramirez, Vanessa I., Awwad, Hibah O., Zaveri, Nurulain T., Toll, Lawrence, Standifer, Kelly M.

Journal:

Journal of Neuroimmune Pharmacology

Year:

2011

Language:

english

File:

PDF, 331 KB

english, 2011

8

Peptidomics of Cpefat/fat mouse brain regions: implications for neuropeptide processing

Xin Zhang, Fa-Yun Che, Iryna Berezniuk, Kemal Sonmez, Lawrence Toll, Lloyd D. Fricker

Journal:

Journal of Neurochemistry

Year:

2008

Language:

english

File:

PDF, 404 KB

english, 2008

9

F.100. Nociceptin/Orphanin FQ Antagonists Ameliorate the Disease Pathogenesis During Inflammatory Bowel Disease

Carsten Alt, Ken Shew, Nahoko Fujita, Thanh-Thuy Tran, Maja Zukic, Willma Polgar, Lawrence Toll, Annalisa D'Andrea

Journal:

Clinical Immunology

Year:

2009

Language:

english

File:

PDF, 39 KB

english, 2009

10

Challenges for opioid receptor nomenclature: IUPHAR Review 9

Cox, Brian M, Christie, Macdonald J, Devi, Lakshmi, Toll, Lawrence, Traynor, John R

Journal:

British Journal of Pharmacology

Year:

2015

Language:

english

File:

PDF, 337 KB

english, 2015

11

Involvement of α4β2 and α3β4 nicotinic receptor subtypes in alcohol taking and seeking

Cippitelli, Andrea, Wu, Jinhua, Debevec, Ginamarie, Armishaw, Christopher, Welmaker, Greg S., Giulianotti, Marc, Toll, Lawrence

Journal:

Year:

2017

Language:

english

File:

PDF, 60 KB

english, 2017

12

Evidence for an NMDA receptor subunit in human keratinocytes and rat cardiocytes

Vera B. Morhenn, Nahid S. Waleh, Jonathan N. Mansbridge, Dennis Unson, Alya Zolotorev, Polly Cline, Lawrence Toll

Journal:

European Journal of Pharmacology: Molecular Pharmacology

Year:

1994

Language:

english

File:

PDF, 627 KB

english, 1994

13

Computer-assisted determination of benzodiazepine receptor heterogeneity

Lawrence Toll, Christopher Keys, Dale Spangler, Gilda Loew

Journal:

European Journal of Pharmacology

Year:

1984

Language:

english

File:

PDF, 460 KB

english, 1984

14

Energy utilization in the uptake of catecholamines by synaptic vesicles and adrenal chromaffin granules

Lawrence Toll, Cameron B. Gundersen Jr., Bruce D. Howard

Journal:

Year:

1977

Language:

english

File:

PDF, 465 KB

english, 1977

15

Computer-assisted analysis of receptor-binding studies of [3H]-naloxone and [3H]-DADL: A reinterpretation of the Na+ effect

Gilda H. Leow, Lawrence Toll, Christopher Keys

Journal:

Year:

1983

Language:

english

File:

PDF, 223 KB

english, 1983

16

Comparative molecular field analysis of fenoterol derivatives: A platform towards highly selective and effective β2-adrenergic receptor agonists

Krzysztof Jozwiak, Anthony Yiu-Ho Woo, Mary J. Tanga, Lawrence Toll, Lucita Jimenez, Joseph A. Kozocas, Anita Plazinska, Rui-Ping Xiao, Irving W. Wainer

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 639 KB

english, 2010

17

[125I]AT-1012, a new high affinity radioligand for the α3β4 nicotinic acetylcholine receptors

Wu, Jinhua, Perry, David C., Bupp, James E., Jiang, Faming, Polgar, Willma E., Toll, Lawrence, Zaveri, Nurulain T.

Journal:

Neuropharmacology

Year:

2014

Language:

english

File:

PDF, 722 KB

english, 2014

18

Anti-nociceptive and anti-allodynic effects of a high affinity NOP hexapeptide [Ac-RY(3-Cl)YRWR-NH2] (Syn 1020) in rodents

Taline V. Khroyan, Willma E. Polgar, Juan Orduna, Naunihal T. Zaveri, Amrit K. Judd, David J. Tuttle, Agustin Sanchez, Lawrence Toll

Journal:

European Journal of Pharmacology

Year:

2007

Language:

english

File:

PDF, 259 KB

english, 2007

19

Replacement of the peptide-backbone amides connecting Tyr-Gly and Gly-Gly in leucine-enkephalin with ketomethylene groups: synthesis and biological activity

Almquist, Ronald G., Olsen, Cris M., Uyeno, Edward T., Toll, Lawrence

Journal:

Journal of Medicinal Chemistry

Year:

1984

Language:

english

File:

PDF, 885 KB

english, 1984

20

Pharmacological stress is required for the anti-alcohol effect of the α3β4* nAChR partial agonist AT-1001

Cippitelli, Andrea, Brunori, Gloria, Gaiolini, Kelly A., Zaveri, Nurulain T., Toll, Lawrence

Journal:

Neuropharmacology

Year:

2015

Language:

english

File:

PDF, 880 KB

english, 2015

21

Synthesis and in vitro biological evaluation of a carbon glycoside analogue of morphine-6-glucuronide

James M. MacDougall, Xiao-Dong Zhang, Willma E. Polgar, Taline V. Khroyan, Lawrence Toll, John R. Cashman

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 119 KB

english, 2005

22

The use of computer analysis in describing multiple opiate receptors

Lawrence Toll, Christopher Keys, Willma Polgar, Gilda Loew

Journal:

Year:

1984

Language:

english

File:

PDF, 243 KB

english, 1984

23

Structural Determinants of Opioid Activity in the Orvinols and Related Structures: Ethers of Orvinol and Isoorvinol

Coop, Andrew, Norton, Claire L., Berzetei-Gurske, Ilona, Burnside, Jackie, Toll, Lawrence, Husbands, Stephen M., Lewis, John W.

Journal:

Journal of Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 146 KB

english, 2000

24

Sub-anesthetic concentrations of (R,S)-ketamine metabolites inhibit acetylcholine-evoked currents in α7 nicotinic acetylcholine receptors

Moaddel, Ruin, Abdrakhmanova, Galia, Kozak, Joanna, Jozwiak, Krzysztof, Toll, Lawrence, Jimenez, Lucita, Rosenberg, Avraham, Tran, Thao, Xiao, Yingxian, Zarate, Carlos A., Wainer, Irving W.

Journal:

European Journal of Pharmacology

Year:

2013

Language:

english

File:

PDF, 463 KB

english, 2013

25

Synthesis and characterization of substituted benzoylhydrazones of naloxone

Grazyna R. Ciszewska, James A. Ginos, Marvin Charton, Kelly M. Standifer, Andrew I. Brooks, George P. Brown, Jennifer P. Ryan-Moro, Ilona Berzetei-Gurske, Lawrence Toll, Gavril W. Pasternak

Journal:

Year:

1996

Language:

english

File:

PDF, 887 KB

english, 1996

26

Structural Determinants of Opioid Activity in the Orvinols and Related Structures. Ethers of 7,8-Cyclopenta-Fused Analogs of Buprenorphine

Andrew Coop, Ilona Berzetei-Gurske, Jackie Burnside, Lawrence Toll, John R. Traynor, Stephen M. Husbands, John W. Lewis

Journal:

Helvetica Chimica Acta

Year:

2000

Language:

english

File:

PDF, 95 KB

english, 2000

27

Desensitization of melanotropin receptors in COS-7 cells

Willma E. Polgar, Catherine M. Bitler, Lawrence Toll

Journal:

Year:

1996

Language:

english

File:

PDF, 555 KB

english, 1996

28

Designing bifunctional NOP receptor–mu opioid receptor ligands from NOP receptor-selective scaffolds. Part I.

Zaveri, Nurulain T., Jiang, Faming, Olsen, Cris, Polgar, Willma E., Toll, Lawrence

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 1.69 MB

english, 2013

29

Discovery of a Potent and Selective α3β4 Nicotinic Acetylcholine Receptor Antagonist from an α-Conotoxin Synthetic Combinatorial Library

Chang, Yi-Pin, Banerjee, Jayati, Dowell, Cheryl, Wu, Jinhua, Gyanda, Reena, Houghten, Richard A., Toll, Lawrence, McIntosh, J. Michael, Armishaw, Christopher J.

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 2.88 MB

english, 2014

30

[IEEE Geoscience and Remote Sensing Symposium, 1992. IGARSS '92. International - Houston, TX, USA (26-29 May 1992)] [Proceedings] IGARSS '92 International Geoscience and Remote Sensing Symposium - Moderate Resolution Imaging Spectroradiometer [modis] And Observations Of The Land Surface

Salomonson, V.V., Toll, D.L., Lawrence, W.T.

Year:

1992

Language:

english

File:

PDF, 362 KB

english, 1992

31

Synthesis of Isohasubanan Alkaloids via Enantioselective Ketone Allylation and Discovery of an Unexpected Rearrangement

Nielsen, Daniel K., Nielsen, Laura L., Jones, Spencer B., Toll, Lawrence, Asplund, Matthew C., Castle, Steven L.

Journal:

Journal of Organic Chemistry

Year:

2009

Language:

english

File:

PDF, 492 KB

english, 2009

32

Effects of addition of a 2-methyl group to ethyl nipecotates (.beta.-meperidines) on receptor affinities and opiate agonist/antagonist activities

Lawson, John A., Cheng, Alice, DeGraw, Joseph, Frenking, Gernot, Uyeno, Edward, Toll, Lawrence, Loew, Gilda H.

Journal:

Journal of Medicinal Chemistry

Year:

1988

Language:

english

File:

PDF, 981 KB

english, 1988

33

The design and synthesis of a novel quinolizidine template for potent opioid and opioid receptor-like (ORL1, NOP) receptor ligands

Ling Jong, Nurulain Zaveri, Lawrence Toll

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 198 KB

english, 2004

34

Novel μ-selective Met-enkephalinamide analogs with antagonist activity. : Synthesis, receptor binding, analgesic properties and conformational studies

AMRIT K. JUDD, JOHN A. LAWSON, CRIS M. OLSEN, LAWRENCE R. TOLL, WILLMA E. POLGAR, EDWARD T. UYENO, CHRISTOPHER J. KEYS, GILDA H. LOEW

Journal:

Chemical Biology & Drug Design

Year:

1987

Language:

english

File:

PDF, 1.27 MB

english, 1987

35

Differential regulation of alcohol taking and seeking by antagonism at α4β2 and α3β4 nAChRs

Cippitelli, Andrea, Brunori, Gloria, Schoch, Jennifer, Armishaw, Christopher J., Wu, Jinhua, Zaveri, Nurulain T., Giulianotti, Marc A., Welmaker, Gregory S., Toll, Lawrence

Journal:

Psychopharmacology

Year:

2018

Language:

english

File:

PDF, 873 KB

english, 2018

36

Dissecting the spinal NOP receptor distribution under a chronic pain model using NOP-eGFP knock-in mice

Ozawa, Akihiko, Brunori, Gloria, Cippitelli, Andrea, Toll, Nicholas, Schoch, Jennifer, Kieffer, Brigitte L, Toll, Lawrence

Journal:

British Journal of Pharmacology

Year:

2018

Language:

english

File:

PDF, 1.58 MB

english, 2018

37

The μ-opioid activity of κ-opioid receptor agonist compounds in the guinea pig ileum

Ilona P. Berzetei-Gurske, Lawrence Toll

Journal:

European Journal of Pharmacology

Year:

1992

Language:

english

File:

PDF, 355 KB

english, 1992

38

Rodent motor and neuropsychological behaviour measured in home cages using the integrated modular platform SmartCage™

Taline V Khroyan, Jingxi Zhang, Liya Yang, Bende Zou, James Xie, Conrado Pascual, Adam Malik, Julian Xie, Nurulain T Zaveri, Jacqueline Vazquez, Willma Polgar, Lawrence Toll, Jidong Fang, Xinmin Xie

Journal:

Clinical and Experimental Pharmacology and Physiology

Year:

2012

Language:

english

File:

PDF, 829 KB

english, 2012

39

Structure-activity studies of β-carboline analogs

John A. Lawson, Edward T. Uyeno, John Nienow, Gilda H. Loew, Lawrence Toll

Journal:

Year:

1984

Language:

english

File:

PDF, 371 KB

english, 1984

40

Mu-Opioid receptor-biased ligands: safe, pain-free analgesics

Madariaga-Mazón, Abraham, Marmolejo-Valencia, Andrés F., Li, Yangmei, Toll, Lawrence, Houghten, Richard A., Martinez-Mayorga, Karina

Journal:

Drug Discovery Today

Year:

2017

Language:

english

File:

PDF, 1.35 MB

english, 2017

41

Retinoic acid (RA) receptor transcriptional activation correlates with inhibition of 12-O-tetradecanoylphorbol- 13-acetate–induced ornithine decarboxylase (ODC) activity by retinoids: A potential role for trans-RA–induced ZBP-89 in ODC inhibition

Marcia I. Dawson, Ju Hui Park, Guo-quan Chen, Wan-ru Chao, Linda Dousman, Nahid Waleh, Peter D. Hobbs, Ling Jong, Lawrence Toll, Xiao-kun Zhang, Jian Gu, Anissa Agadir, Juanita L. Merchant, Longchuan

Journal:

International Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 322 KB

english, 2001

42

Activity of new NOP receptor ligands in a rat peripheral mononeuropathy model: Potentiation of morphine anti-allodynic activity by NOP receptor antagonists

Taline V. Khroyan, Willma E. Polgar, Juan Orduna, Faming Jiang, Cris Olsen, Lawrence Toll, Nurulain T. Zaveri

Journal:

European Journal of Pharmacology

Year:

2009

Language:

english

File:

PDF, 326 KB

english, 2009

43

Characterization of the δ receptor subtype in SH-SY5Y neuroblastoma cells

Lawrence Toll, Willma E. Polgar, Jane S. Auh

Journal:

Regulatory Peptides

Year:

1994

Language:

english

File:

PDF, 140 KB

english, 1994

44

Modulation of enkephalin release by nociceptin (orphanin FQ)

Alan R Gintzler, Indira D Adapa, Lawrence Toll, Victor M Medina, Lin Wang

Journal:

European Journal of Pharmacology

Year:

1997

Language:

english

File:

PDF, 171 KB

english, 1997

45

Synthesis and antitubercular activity of phenothiazines with reduced binding to dopamine and serotonin receptors

Peter B. Madrid, Willma E. Polgar, Lawrence Toll, Mary J. Tanga

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 162 KB

english, 2007

46

Molecular determinants of recognition and activation at the μ-opioid receptor by met-enkephalin-like peptides

Juan J. Perez, Hugo O. Villar, Ed Uyeno, Lawrence Toll, Christopher Olsen, Wilma Polgar, Gilda H. Loew

Journal:

International Journal of Quantum Chemistry

Year:

1993

Language:

english

File:

PDF, 891 KB

english, 1993

47

Varenicline decreases nicotine but not alcohol self-administration in genetically selected Marchigian Sardinian alcohol-preferring (msP) rats

Scuppa, Giulia, Cippitelli, Andrea, Toll, Lawrence, Ciccocioppo, Roberto, Ubaldi, Massimo

Journal:

Drug and Alcohol Dependence

Year:

2015

Language:

english

File:

PDF, 891 KB

english, 2015

48

μ-Opioid receptor binding in intact SH-SY5Y neuroblastoma cells

Journal:

European Journal of Pharmacology

Year:

1990

Language:

english

File:

PDF, 303 KB

english, 1990

49

Regulation of transcription of the human prepronociceptin gene by Sp1

Naunihal T. Zaveri, Christopher J. Green, Willma E. Polgar, Nhung Huynh, Lawrence Toll

Journal:

Year:

2002

Language:

english

File:

PDF, 286 KB

english, 2002

50

A novel G proteinâbiased agonist at the Î¼ opioid receptor induces substantial receptor desensitization through G proteinâcoupled receptor kinase

Groom, Sam, Blum, Nina K., Conibear, Alexandra E., Disney, Alexander, Hill, Rob, Husbands, Stephen M., Li, Yangmei, Toll, Lawrence, Kliewer, Andrea, Schulz, Stefan, Henderson, Graeme, Kelly, Eamonn, B

Journal:

British Journal of Pharmacology

Year:

2020

File:

PDF, 1.62 MB

2020

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